| The Venus flower basket structure, which lives in the deep sea, has characteristics such as light weight, high strength, good pressure resistance and so on, making it a kind of typical lightweight and high-strength biological structure. In this paper, we propose a pressure-resistant shell structure design inspired by the structure of the Venus's Flower Basket and conduct a numerical simulation study on its pressure resistance performance. Using the 240mm compartment section as the standard, under the condition of the same volume, length, outer diameter, and external water pressure, the pressure resistant performance of conventional underwater vehicle shell structures, two diagonal reinforced shell structures, and the Venus flower basket-inspired shell structure are compared and analyzed. The results show that the Venus flower basket-inspired structure has the best strength performance, with the smallest maximum stress and principal stress. The proposed biomimetic structure is of great significance for innovative design of underwater vehicles.